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Bill Maher CBD Oil Unfortunately these have lots of side effects as they increase risk of stroke and heart attack. So people are seeking safer, natural alternatives such as glucosamine, chondroitin, turmeric, SAMe, MSM and fish oil to treat their painful symptoms. After all Nature has reserved every thing for its creations. Hence we should opt for natural remedies as it is said, Back pain at night is a common experience that bothers thousands of people around the world.